RegenPRP™
The standardised leucocyte-reduced
platelet concentrate prepared with
RegenLab® technology that provides
an autologous reservoir of growth factors.
What is RegenPRP™ ?
1.1 – Platelets
In addition to their role in haemostasis, platelets are key factors in tissue repair mechanisms.1 They provide essential growth factors, such as FGF, PDGF, TGF-β, EGF, VEGF, IGF, which are involved in stem cell migration, differentiation, and proliferation. Platelet growth factors also stimulate fibroblasts and endothelial cells to induce the deposition of new extracellular matrix and neo-vascularisation, respectively.
1.2 – Plasma
Plasma contains many factors essential for cell survival including nutrients, vitamins, hormones, electrolytes, growth factors (such as IGF and HGF), and proteins. Among the plasma proteins, the molecules involved in the coagulation process allow the formation of the fibrin polymer that serves as a scaffold for cell migration and new tissue generation.2
1.3 – Platelet Rich Plasma (PRP)
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Proven efficacy in tissue healing, with key roles in cell migration, proliferation, and differentiation
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Mechanism of action comprises anti-inflammatory activity and activation of cell-signalling cascades
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Key role in the synthesis of new extracellular matrix for tissue regeneration
Technology advantages
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User-independent standardised preparation
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Minimum volume of blood required
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Safe closed-circuit system
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Mechanical separation of PRP using a chemically inert separator gel with a single centrifugation at a relative centrifugal force of 1500 x g
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Pharmaceutical grade solution of sodium citrate allowing a reversible anticoagulation
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Addition of Autologous Thrombin Serum (ATS prepared with RegenATS™ device), either alone or combined with a calcium solution, allows to obtain RegenPRP™ in different jellified forms
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Minimal learning curve and ease of use
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Operationally and clinically efficient process
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Facilitates and streamlines routine practice
Scientific advantages
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Demonstrated safety and efficacy
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Evidence-based outcomes for numerous therapeutic indications
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Large number of clinical studies, with over 200 publications
Biological advantages
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RegenPRP™ is standardised, leucocyte-reduced and easily reproducible
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RegenLab® specific separator gel technology guarantees minimal variability
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Platelet recovery > 80%
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High platelet quality. Viable & functional platelets
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Full plasma recovery. No loss of plasma growth factors and fibrinogen
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Leucocyte-reduced PRP. Depletion of ~ 96% of pro-inflammatory granulocytes, leaving mainly lymphocytes and monocytes
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Virtually no red blood cells. Depletion of ~ 99.7% of erythrocytes
Technology advantages
The technology ensures consistent PRP preparation with minimal blood, using a safe, closed system and inert separator gel after a quick 5-minute centrifugation at 1500g. It includes pharmaceutical-grade sodium citrate for reversible anticoagulation, is easy to use with minimal training, and streamlines routine clinical practice efficiently.
Biological advantages
RegenLab®'s separator gel ensures reproducible results with over 80% platelet recovery, high platelet quality, full plasma recovery, and minimal red blood cells. It produces leucocyte-reduced PRP, preserving essential growth factors and fibrinogen.
Scientific advantages
The technology's scientific advantages include demonstrated safety and efficacy, with evidence-based outcomes for various therapeutic indications. Supported by over 200 clinical studies, it has a robust foundation of research confirming its effectiveness.
Since 2003, Regen Lab SA has been committed to the development of a unique expertise for the design and manufacturing of high-quality medical devices.