Technology
The simple, safe & efficient point of care preparation of autologous platelet rich plasma
Device Technology
All Regen™ tubes consist of pharmaceutical-grade class I borosilicate and use vacuum for automated blood collection. The hallmark of the Regen™ technology is a thixotropic separating gel composed of a mixture of polymers for gravimetric plasma separation (elimination of RBC and WBC). RegenTHT, Regen BCT and A-CP are devices designed for the preparation of PRP and contain a sodium citrate anticoagulant solution above the separating gel. The RegenATS device does not contain anticoagulant. In this device, the plasma coagulates and a serum rich in activated thrombin is extracted from the plasma clot.
Regen Lab devices intended for PRP preparation consist of evacuated glass tubes containing a thixotropic gel with a specific density designed for platelet or platelet and MNC isolation, and anticoagulant solution. The gel acts as a mechanical separator of blood components, and sodium citrate solution as blood anticoagulant. Thixotropy is a physical property of some gels which are thick under static condition, become more fluid when submitted to physical stress (in this case, the centrifugal force) and regain their original consistency when the physical stress stops.
How it works
Thanks to the vacuum system, blood is gently collected into the tube and mixed with an anticoagulant by gentle inversion. The blood-filled device is centrifuged at 1500 g for 5 (A-CP and Regen BCT) or 9 minutes (RegenTHT). During centrifugation, the thixotropic separator gel becomes fluid and migrates upwards, while red and white blood cells move downwards. The gel forms a solid barrier, isolating platelets and plasma above it, while trapping RBC and most WBC below.
After centrifugation, platelets form a thin layer on the gel’s surface. To resuspend the platelets in the plasma, the tube is gently inverted repeatedly. The PRP is then collected using a blood transfer device and syringe, ready for physician use. This automated process ensures reliable and reproducible PRP isolation with high platelet recovery and low contamination levels, independent of the operator.
Preparation Process
- Collection: Blood is drawn into evacuated pharmaceutical grade borosilicate tubes containing an anticoagulant solution and separating polymer gel.
- Mixing: The blood is gently mixed with the anticoagulant by
gentle inversion of the tube. - Centrifugation: The tube is centrifuged for 5 to 9 minutes, depending on the model and gel type, using either a tabletop centrifuge with a fixed angle rotor or a larger centrifuge with a swing-out horizontal rotor.
Simple | Safe | Efficient
Advantages of Regen Lab Technology
Regen Lab Technology is known for its advancements in regenerative medicine and biotechnology.
Minimally Invasive:
Treatments using Regen Lab Technology are typically minimally invasive, reducing the need for extensive surgery and allowing for quicker recovery times.
Enhanced Healing and Recovery:
PRP and similar therapies can accelerate the healing process for various conditions, including sports injuries, osteoarthritis, and chronic wounds, by enhancing the body’s natural healing mechanisms.
Reduced Risk of Rejection:
Since the treatments often use the patient’s own cells and blood components, there is a lower risk of rejection or adverse reactions, ensuring a safer therapeutic approach.
Versatility:
Regen Lab Technology can be applied across a wide range of medical fields, including orthopedics, dermatology, aesthetics, and dental medicine, making it a versatile tool in modern healthcare.
Customization:
The technology allows for personalized treatment plans tailored to the specific needs of each patient, leading to more effective outcomes.
Cost-Effective:
Compared to some traditional treatments and surgeries, regenerative therapies can be more cost-effective in the long run due to quicker recovery times and reduced need for additional interventions.
Regulatory Approval:
Many of Regen Lab’s products have received regulatory approval from agencies such as the FDA and CE, ensuring compliance with high standards of safety and efficacy.
Patient Satisfaction:
High levels of patient satisfaction are reported due to the natural and lasting results of regenerative treatments, contributing to an overall improved quality of life.